Mechanical Influence of Edentulous Mandibular Morphology on Peri-implant Bone in Implant Prosthetics: Threedimensional Finite Element Analysis.

PURPOSE: The purpose of this study was to examine the mechanical influence of edentulous mandibular morphology on peri-implant bone in implant prosthetics by finite element analysis. MATERIALS AND METHODS: Computed tomographic data from 25 patients with edentulous mandibles were selected and the radius of mandibular curvature and the height of the mandible at the midline were measured in order to clarify the morphological characteristics of the mandible. From the measurement, two patients with the smallest and largest radii of the mandible were selected. Two types of three-dimensional finite element models consisting of the edentulous mandible (small and large radius), superstructure (a cantilever bridge), implants, and abutments were created. Four implants were inserted between the right and left mental foramina. The upper surface of the mandibular condyle was constrained, and a vertical load of 100 N was applied on the occlusal surface of the right first molar. Three-dimensional finite element analysis of each model was performed to examine the mechanical influence of the edentulous mandibular morphology on the peri-implant bone. RESULTS: Measurement of mandibular morphology in CT images indicated that the lower the mandibular height was, the larger was the radius of the anterior mandibular curvature. Finite element analysis revealed that a higher equivalent stress was generated in the peri-implant bone of the model with a larger radius of curvature than that of the model with a smaller radius of curvature. The highest equivalent stress in the mandible was generated in the distal margin of the peri-implant bone posterior to the loaded side of the large radius of curvature model. CONCLUSIONS: The mandibular morphology had a mechanical influence on the peri-implant bone.

A posterior tibial slope angle over 12 degrees is critical to epiphyseal fracture of the proximal tibia: Three-dimensional finite element analysis.

Introduction: The effects of the proximal tibial slope angle on the proximal tibial epiphysis remain unknown. To elucidate those effects, we investigated the strain distribution in proximal tibial epiphysis with different proximal tibial slope angles and proximal tibial epiphysis closure periods using finite element analysis. Materials and methods: The finite element models of the proximal tibia were reconstructed from CT images and consisted of cancellous/cortical bone and epiphyseal plate. The variations in proximal tibial slope angle (range: 6-16°) and four closure variations in proximal tibial epiphysis (open, semi-open, semi-closed, and closed) were prepared. The loading force on the medial and lateral joint surface, and the tensile force by the patellar tendon were applied to the models, and the distal area of the tibia was fixed. The ratio of the equivalent strain in semi-open/semi-closed proximal tibial epiphysis to the strain in open proximal tibial epiphysis on different proximal tibial slope angles were calculated. Results: The strain ratio between the semi-open/semi-closed and open proximal tibial epiphysis models indicated significant differences between 6 or 8° of proximal tibial slope angle and 12, 14, and 16° of proximal tibial slope angle models. In the increased proximal tibial slope angle model, a hoop-shaped strain in the closing proximal tibial epiphysis was found, and the maximum strain was found in the tibial tubercle. Discussion: During epiphyseal closure, adolescents with an increased proximal tibial slope angle over 12° are significantly at risk for suffering from proximal tibial epiphyseal fractures compared with those under 10°.

Finite-Element Analysis of Stress on the Proximal Tibia After Unicompartmental Knee Arthroplasty.

BACKGROUND: Because the indications for unicompartmental knee arthroplasty (UKA) are limited, few patients have undergone the procedure. Therefore, it is difficult to decide the acceptable range of variation in the details of UKA on the basis of the available clinical data. The objective of this study was to identify factors that affect the distribution of stress on the proximal tibia after UKA. METHODS: Two-dimensional finite-element analysis of the proximal tibia was used to assess four factors: 1) two types of implants-all ultra-high-molecular-weight polyethylene (UHMWPE) and metal-backed implants, 2) postoperative alignment, 3) coverage of tibial bone, 4) level of the tibial osteotomy. RESULTS: In cases of varus alignment, high stress values and large areas of deformation were observed on and beneath the implant. In cases of valgus alignment, stress was concentrated at the lateral portion of tibial tray. In comparison with the standard model, stress concentration was greater at the medial edge of the medial condyle in a narrow-coverage model. Stress distribution for the low-osteotomy-level model did not differ markedly differ from that for the standard model. Stress distribution was better for metal-backed implants than for UHMWPE implants. CONCLUSIONS: Proper postoperative alignment must be achieved in UKA. The osteotomy level should be set at the cancellous bone close to the joint line, and preservation of bone stock should be maximized.

Three-Dimensional Finite Analysis of the Optimal Alignment of the Tibial Implant in Unicompartmental Knee Arthroplasty.

BACKGROUND: Although unicompartmental knee arthroplasty (UKA) has become more common because of its good outcomes, several complications have been reported. Tibial implant alignment, an important cause of such complications, has been investigated; however, the optimal alignment of the tibial implant has not been determined. This study used 3-dimensional finite element analysis to investigate changes in stress distribution in the proximal tibia after UKA at multiple tibial implant alignments. METHODS: A 3-dimensional finite element model was created with CT digital imaging and communications in medicine (CT-DICOM) data from a medial osteoarthritic knee. Change in stress distribution of the tibial implant alignment on the coronal plane (middle position, varus 5°, valgus 5°) and sagittal plane (0°, 5°, 10°) under conditions of a loose boundary between implant and bone and no loosening was analyzed with 3-dimensional finite analysis. RESULTS: In the absence of loosening, the stress distribution was high at the lateral rim of the subchondral bone in the varus alignment model, and the high stress distribution moved from the anterior to the posterior position with posterior tilting from 0° to 10°. With loosening, the stress distribution was high at the proximal tibial medial cortex in the valgus alignment model. CONCLUSIONS: To reduce UKA complications, the present findings indicate that the optimal alignment of the tibial implant is at the middle position on the coronal plane, with a posterior inclination similar to the original inclination on the sagittal plane.

Ex-vivo observation of calcification process in chick tibia slice: Augmented calcification along collagen fiber orientation in specimens subjected to static stretch.

Bone formation through matrix synthesis and calcification in response to mechanical loading is an essential process of the maturation in immature animals, although how mechanical loading applied to the tissue increases the calcification and improves mechanical properties, and which directions the calcification progresses within the tissue are largely unknown. To address these issues, we investigated the calcification of immature chick bone under static tensile stretch using a newly developed real-time observation bioreactor system. Bone slices perpendicular to the longitudinal axis obtained from the tibia in 2- to 4-day-old chick legs were cultured in the system mounted on a microscope, and their calcification was observed up to 24 h while they were stretched in the direction parallel to the slice. Increase in the calcified area, traveling distance and the direction of the calcification and collagen fiber orientation in the newly calcified region were analyzed. There was a significant increase in calcified area in the bone explant subjected to tensile strain over ∼3%, which corresponds to the threshold strain for collagen fibers showing alignment in the direction of stretch, indicating that the fiber alignment may enhance tissue calcification. The calcification progressed to a greater distance to the stretching direction in the presence of the loading. Moreover, collagen fiber orientation in the calcified area in the loaded samples was coincided with the progression angle of the calcification. These results clearly show that the application of static tensile strain enhanced tissue calcification, which progresses along collagen fibers aligned to the loading direction.

Three-dimensional modeling of removal torque and fracture progression around implants.

In the present study, a model for simulations of removal torque experiments was developed using finite element method. The interfacial retention and fracturing of the surrounding material caused by the surface features during torque was analyzed. It was hypothesized that the progression of removal torque and the phases identified in the torque response plot represents sequential fractures at the interface. The 3-dimensional finite element model fairly accurately predicts the torque required to break the fixation of acid-etched implants, and also provides insight to how sequential fractures progress downwards along the implant side.

Understanding mechanisms and factors related to implant fixation; a model study of removal torque.

Osseointegration is a prerequisite for achieving a stable long-term fixation and load-bearing capacity of bone anchored implants. Removal torque measurements are often used experimentally to evaluate the fixation of osseointegrated screw-shaped implants. However, a detailed understanding of the way different factors influence the result of removal torque measurements is lacking. The present study aims to identify the main factors contributing to anchorage. Individual factors important for implant fixation were identified using a model system with an experimental design in which cylindrical or screw-shaped samples were embedded in thermosetting polymers, in order to eliminate biological variation. Within the limits of the present study, it is concluded that surface topography and the mechanical properties of the medium surrounding the implant affect the maximum removal torque. In addition to displaying effects individually, these factors demonstrate interplay between them. The rotational speed was found not to influence the removal torque measurements within the investigated range.